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MR Imaging of Creutzfeldt-Jakob Disease Radiology 199:793-798, Finkenstaedt,M.,et al, 1996 See this aricle in Pubmed Article Abstract Although approximately 20%of the patients did not have MR imaging abnormalities,MR imaging did show signal intensity alterations due to gliosis and spongiform changes early in the course of CJD in the remaining 80%.The demonstration of bilateral areas of increased signal intensity that predominantly affected the caudate nuclei and the putamina on long- repetition-time MR images in an elderly patient with rapidly progressive dementia represents a specific finding and clearly should suggest the diagnosis of CJD.

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